
Albendazole is an anti-parasitic prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of two parasitic infections: neurocysticercosis and hydatid disease.
Albendazole is also used to treat a parasitic infection called microsporidiosis. Microsporidiosis can be an opportunistic infection (OI) of HIV. An OI is an infection that occurs more frequently or is more severe in people with weakened immune systemssuch as people with HIVthan in people with healthy immune systems.
Albendazole is a broad-spectrum, synthetic benzimidazole-derivative anthelmintic. Albendazole interferes with the reproduction and survival of helminths by inhibiting the formation of microtubules from tubulin. This leads to an impaired uptake of glucose, a depletion of glycogen stores, and results in the worm's death. Albendazole is used in the treatment of dog and pork tapeworm-causing diseases, including hydatid disease and neurocysticercosis. Albendazole may also be used to treat a variety of other roundworm infections.
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